Ciapponi, Agustín (2020) Clinical question: For individuals with opiate use disorders, what are the effects of dihydrocodeine for detoxification? Cochrane Clinical Answers, DOI: 10.1002/cca.3041.
External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...
Compared with buprenorphine, low‐certainty evidence suggests that dihydrocodeine for detoxification of individuals with opiate use disorders may increase the number of people who discontinue treatment (on average, 70 more people per 1000). Furthermore, effects on abstinence and on overdose are too imprecise to suggest a direction of effect. Two RCTs involving 105 participants reported no deaths and no other adverse events.
B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
HJ Treatment or recovery method > Substance disorder treatment method
HJ Treatment or recovery method > Substance disorder treatment method > Substance disorder drug therapy (pharmacological treatment)
HJ Treatment or recovery method > Substance disorder treatment method > Detoxification
HJ Treatment or recovery method > Treatment outcome
VA Geographic area > International
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